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Viewbox scales things too small at high resolutions and scale factors and they are virtually impossible to see

I have a grid with one row and some columns. In order to scale correctly the grid content according to the screen resolution and scale selected in the Windows OS, I use a Viewbox.
I also define a style that is applied to all Viewboxes:
<Style TargetType="{x:Type Viewbox}">
<Setter Property="Stretch" Value="Uniform"/>
<Setter Property="StretchDirection" Value="Both"/>
<Setter Property="HorizontalAlignment" Value="Left"/>
<Setter Property="VerticalAlignment" Value="Center"/>
<Setter Property="OverridesDefaultStyle" Value="False"/>
<Setter Property="UseLayoutRounding" Value="False"/>
</Style>
And then I enclose every grid column within a Viewbox:
<Grid Focusable="True"
Height="Auto">
<Grid.ColumnDefinitions>
<!-- Animated image -->
<ColumnDefinition Width="Auto" />
<!-- Stack panel with icon and text -->
<ColumnDefinition Width="Auto" />
<!-- A vertical separator -->
<ColumnDefinition Width="Auto" />
<!-- A button -->
<ColumnDefinition Width="Auto" />
<!-- Empty dummy column to help distribute space correctly between columns so it will cause next columns to be horizontally right aligned. -->
<ColumnDefinition Width="*" />
<!-- Help button -->
<ColumnDefinition Width="Auto" />
<!-- Three dots button -->
<ColumnDefinition Width="Auto"/>
</Grid.ColumnDefinitions>
<Viewbox Grid.Column="0">
<StackPanel Orientation="Horizontal"
Visibility="{Binding Path=IsAnimatedImgVisible, Converter={StaticResource BoolToVisibility}}">
<v:UserControlAnimatedImg x:Name="UcSpinner" VerticalAlignment="Center" HorizontalAlignment="Left"/>
<Label SnapsToDevicePixels="True"
RenderOptions.BitmapScalingMode="HighQuality"
VerticalAlignment="Center" HorizontalAlignment="Left"
Content="{Binding Path=StatusText}"/>
</StackPanel>
</Viewbox>
<Viewbox Grid.Column="1">
<StackPanel Orientation="Horizontal">
<Image
Margin="10,5"
Height="24"
Width="24"
MaxHeight="24"
MaxWidth="24"
VerticalAlignment="Center"
HorizontalAlignment="Center"
SnapsToDevicePixels="True"
RenderOptions.BitmapScalingMode="HighQuality"
Source="{Binding Path=Icon}"/>
<Label
VerticalAlignment="Center"
HorizontalAlignment="Left"
Content="{Binding Path=StatusTxt}"
SnapsToDevicePixels="True"
RenderOptions.BitmapScalingMode="HighQuality">
</Label>
</StackPanel>
</Viewbox>
<Viewbox Grid.Column="2">
<Separator Margin="10,5,5,5"
Height="26"
Style="{StaticResource {x:Static ToolBar.SeparatorStyleKey}}">
</Viewbox>
<Viewbox Grid.Column="3">
<Button Height="Auto"
Width="150"
Command="{Binding ButtonOnClick}">
<StackPanel Orientation="Horizontal">
<Image
Height="24"
Width="25"
MaxHeight="24"
MaxWidth="25"
VerticalAlignment="Center"
HorizontalAlignment="Center"
SnapsToDevicePixels="True"
RenderOptions.BitmapScalingMode="HighQuality"
Source="{Binding ImageIcon}"/>
<TextBlock
Margin="10,2,5,2"
VerticalAlignment="Center"
HorizontalAlignment="Left"
Text="{x:Static p:Resources.BtnText}"
SnapsToDevicePixels="True"
RenderOptions.BitmapScalingMode="HighQuality">
</TextBlock>
</StackPanel>
</Button>
</Viewbox>
<!-- Empty dummy space to help distribute space correctly between columns and
make next columns to be horizontally right aligned. This column will be blank
space.-->
<Viewbox Grid.Column="4">
<ContentControl />
</Viewbox>
<Viewbox Grid.Column="5">
<Button Height="25"
Width="25"
MaxHeight="25"
MaxWidth="25"
Margin="8,0,5,0"
Style="{StaticResource {x:Static ToolBar.ButtonStyleKey}}"
Command="{Binding BtnHlpClick}">
<Image HorizontalAlignment="Center"
VerticalAlignment="Center"
SnapsToDevicePixels="True"
RenderOptions.BitmapScalingMode="HighQuality"
Source="{Binding ImageHelpIcon}"/>
</Button>
</Viewbox>
<Viewbox Grid.Column="6">
<StackPanel x:Name="PlaceHolder"
VerticalAlignment="Center"
Margin="2,0,12,0"
Width="27"
Height="Auto">
<Image HorizontalAlignment="Center"
VerticalAlignment="Center"
Height="20"
Width="20"
SnapsToDevicePixels="True"
RenderOptions.BitmapScalingMode="HighQuality"
Source="{Binding ImgThreeDotsIcon}">
<Image.ContextMenu>
<ContextMenu Placement="Bottom" Background="#FFFFFF">
<MenuItem Header="{x:Static p:Resources.mnutext}" Command="{Binding MenuOnClick}"></MenuItem>
</ContextMenu>
</Image.ContextMenu>
</Image>
</StackPanel>
</Viewbox>
The problem I am currently facing is that when I switch to high screen resolutions and also I switch to high scale factor (125%, 150%, 175%, 200%, and so on), then the content of the grid is getting smaller and smaller and it is practically impossible to see. The more screen resolution I select, the more smaller is the grid content. The more scale factor I select, the more smaller is the grid content. The problem is that the grid content gets too small and impossible to see.
How can I solve this?

Resize Images inside grid - WPF

I have to show three images in a way that center image should have double width of left or right end views. The Imagesource to Left and right end have size of 335x377 and the center imagesource have size of 403x226.
<Grid x:Name="LayoutRoot" Background="Black">
<Grid.RowDefinitions>
<RowDefinition Height="*"></RowDefinition>
</Grid.RowDefinitions>
<Grid.ColumnDefinitions>
<ColumnDefinition Width="0.5*" ></ColumnDefinition>
<ColumnDefinition Width="*" ></ColumnDefinition>
<ColumnDefinition Width="0.5*" ></ColumnDefinition>
</Grid.ColumnDefinitions>
<StackPanel Grid.Row="0" Grid.Column="0" HorizontalAlignment="Center" Background="Blue" VerticalAlignment="Center" >
<Image Name="ImageViewer1" Stretch="None" />
</StackPanel>
<StackPanel Grid.Row="0" Grid.Column="1" HorizontalAlignment="Center" Background="Yellow" VerticalAlignment="Center" >
<Image Name="ImageViewer2" Stretch="None" />
</StackPanel>
<StackPanel Grid.Row="0" Grid.Column="2" HorizontalAlignment="Center" Background="Red" VerticalAlignment="Center" >
<Image Name="ImageViewer3" Stretch="None" />
</StackPanel>
</Grid
Shall I need to define the size of 'ImageViewer' to achieve this ?

Unless the image widths do not more or less exactly match the column widths, it is obviously wrong to set
<Image Stretch="None" ... />
You would either set
<Image Stretch="Uniform" ... />
to make the left and right images horizontally fill their columns, or
<Image Stretch="UniformToFill" ... />
to make them also fill the row height, but cut off a bit at their sides.
You could also remove the StackPanels:
<Grid>
...
<Image x:Name="ImageViewer1" Grid.Column="0" Stretch="UniformToFill" />
<Image x:Name="ImageViewer2" Grid.Column="1" Stretch="UniformToFill" />
<Image x:Name="ImageViewer3" Grid.Column="2" Stretch="UniformToFill" />
</Grid>

WPF Window resize "eats" controls width

I have an issue im struggling a day now. Im trying to center some controls into a Grid layout. I have 2 columns and i want half of the controls centered ad the 1st column and other half to the second column
When the window resize some of them get "eaten" on the edges , and i wasent able to identify the issue
Can anyone spot the issue?
<Grid Margin="0,2,0,-2">
<Grid.RowDefinitions>
<RowDefinition Height="*"/>
</Grid.RowDefinitions>
<Grid.ColumnDefinitions>
<ColumnDefinition Width="*" />
<ColumnDefinition Width="*" />
</Grid.ColumnDefinitions>
//.......
<ComboBox x:Name="optMenuLeft" Margin="0,271,0,0" VerticalAlignment="Top" Height="26" HorizontalAlignment="Center" Width="170" Grid.RowSpan="2" />
<Label Content="Menu" Margin="141,271,390,0" VerticalAlignment="Top" HorizontalContentAlignment="Right" HorizontalAlignment="Center" Width="69" Grid.RowSpan="2" />
<ComboBox x:Name="optBedOccupancyLeft" VerticalAlignment="Top" Height="26" Grid.RowSpan="2" HorizontalAlignment="Center" Width="170" Margin="0,240,0,0"/>
<Label Content="Bed Occupancy" Margin="0,240,270,0" VerticalAlignment="Top" HorizontalContentAlignment="Right" Grid.RowSpan="2" HorizontalAlignment="Center" Width="94"/>
//.......
<ComboBox Name="optMenuRight" Margin="255,271,175,0" Grid.Column="1" VerticalAlignment="Top" Height="26" HorizontalAlignment="Center" Width="170"/>
<Label Content="Menu" Margin="176,271,353,0" Grid.Column="1" VerticalAlignment="Top" HorizontalContentAlignment="Right" HorizontalAlignment="Center" Width="71"/>
<ComboBox Name="optBedOccupancyRight" Margin="255,240,175,0" Grid.Column="1" VerticalAlignment="Top" Height="26" HorizontalAlignment="Center" Width="170" Grid.RowSpan="2"/>
<Label Content="Bed Occupancy" Grid.Column="1" Margin="0,240,200,0" VerticalAlignment="Top" HorizontalContentAlignment="Right" Grid.RowSpan="2" HorizontalAlignment="Center" Width="94"/>
//.....

The simplest way is to use grids inside grid. The outer grid will split the window into two columns. The inner grids will split the columns into four cells (2x2). Just center the inner grids and it will work like a charm.
<Grid x:Name="LayoutRoot">
<Grid.ColumnDefinitions>
<ColumnDefinition />
<ColumnDefinition />
</Grid.ColumnDefinitions>
<Grid x:Name="LeftColumn" VerticalAlignment="Center" HorizontalAlignment="Center">
<Grid.ColumnDefinitions>
<ColumnDefinition Width="Auto"/>
<ColumnDefinition />
</Grid.ColumnDefinitions>
<Grid.RowDefinitions>
<RowDefinition />
<RowDefinition />
</Grid.RowDefinitions>
<Label Content="Bed Occupancy" />
<ComboBox x:Name="optBedOccupancyLeft" Grid.Column="1" />
<Label Content="Menu" Grid.Row="1"/>
<ComboBox x:Name="optMenuLeft" Grid.Column="1" Grid.Row="1" />
</Grid>
<Grid x:Name="RightColumn" VerticalAlignment="Center" HorizontalAlignment="Center>
<!-- the same as left column -->
</Grid>
</Grid>
Btw, notice, that when you want split some are to equal columns (or rows or both), you can use UniformGrid:
<UniformGrid x:Name="LayoutRoot" Rows="1">
<Grid x:Name="LeftColumn" />
<Grid x:Name="RightColumn" />
</UniformGrid>

There is also more advanced approach that I often use:
Use UniformGrid to define columns. The xaml is smaller and cleaner.
Use HeaderedContentControl to define labels and inputs
Use Grid's SharedSizeScope feature, to make width of label equal: https://msdn.microsoft.com/en-us/library/system.windows.controls.grid.issharedsizescope%28v=vs.110%29.aspx
<UniformGrid x:Name="LayoutRoot" Rows="1">
<StackPanel x:Name="LeftColumn" Grid.IsSharedSizeScope="True"
HorizontalAlignment="Center" VerticalAlignment="Center">
<HeaderedContentControl Header="Bed Occupancy" Style="{StaticResource LabelValueContentControl}">
<ComboBox x:Name="optBedOccupancyLeft" />
</HeaderedContentControl>
<HeaderedContentControl Header="Menu" Style="{StaticResource LabelValueContentControl}" >
<ComboBox x:Name="optMenuLeft" />
</HeaderedContentControl>
</StackPanel>
<StackPanel x:Name="RightColumn" Grid.IsSharedSizeScope="True">
<!-- the same as left column -->
</StackPanel>
</UniformGrid>
The LabelCalueControlStyle is take advantage of shared column size
<Style x:Key="LabelValueContentControl" TargetType="HeaderedContentControl">
<Setter Property="Padding" Value="5" />
<Setter Property="Template">
<Setter.Value>
<ControlTemplate TargetType="HeaderedContentControl">
<Grid>
<Grid.ColumnDefinitions>
<ColumnDefinition Width="Auto" SharedSizeGroup="LabelValueContentControl.Label" />
<ColumnDefinition Width="*" />
</Grid.ColumnDefinitions>
<ContentPresenter ContentSource="Header"
Margin="{TemplateBinding Padding}"
HorizontalAlignment="Right" />
<ContentPresenter Grid.Column="1" Margin="{TemplateBinding Padding}" />
</Grid>
</ControlTemplate>
</Setter.Value>
</Setter>
</Style>

Xaml, middle column not taking up full width

How do I make my middle column take up the full width available while allowing space for the comment section so that all those comment boxes are nicely aligned to the right:
<DataTemplate x:Key="ActivityStreamItemTemplate">
<StackPanel VerticalAlignment="Top" Margin="5,0,0,0">
<Button Command="{Binding Path=DataContext.LoadSpacesCommand, ElementName=OrganisationList}" CommandParameter="{Binding}" Padding="-5,0,-5,-5" Margin="-7,-12,-7,-7" Height="auto" BorderThickness="0" HorizontalAlignment="Left" VerticalAlignment="Stretch" HorizontalContentAlignment="Left" UseLayoutRounding="True" FontSize="0.01">
<Grid Height="auto">
<Grid.ColumnDefinitions>
<ColumnDefinition Width="67" />
<ColumnDefinition Width="*"/>
<ColumnDefinition Width="60" />
</Grid.ColumnDefinitions>
<StackPanel Height="auto" Grid.Column="0" Background="Transparent">
<Border Background="Transparent" BorderThickness="0" Width="62" Height="62" HorizontalAlignment="Left" Margin="0,0,0,5">
<Image Source="{Binding created_by.image.link}" Width="62" Height="62"></Image>
</Border>
</StackPanel>
<StackPanel Height="auto" Grid.Column="1">
<TextBlock Text="{Binding type}" HorizontalAlignment="Left" FontSize="30" VerticalAlignment="Center" Margin="0,0,0,5" Foreground="White" />
<TextBlock Text="{Binding ttitle}" HorizontalAlignment="Left" FontSize="15" VerticalAlignment="Center" Margin="0,0,0,5" Foreground="White" TextWrapping="Wrap"/>
<TextBlock Text="{Binding created_by.name}" HorizontalAlignment="Left" FontSize="11" VerticalAlignment="Center" Margin="0,0,0,5" Foreground="White" />
</StackPanel>
<StackPanel Height="60" Grid.Column="2" Margin="10,0,0,0">
<StackPanel.Background>
<ImageBrush Stretch="Fill" ImageSource="/Assets/Icons/CommentsIcon.png"/>
</StackPanel.Background>
<TextBlock Text="{Binding comments.Count}" HorizontalAlignment="Center" FontSize="20" Foreground="Black" TextAlignment="Center" Padding="0,8,0,0"/>
</StackPanel>
</Grid>
</Button>
</StackPanel>
</DataTemplate>
I tried placing horizontal align on the third stackpanel but that actually didn't work.
EDIT: Thanks for the tries but no cigar:

You need to alter the style of the ListBoxItem itself to ensure that the content is stretched across the available width.
Define this style:
<Style x:Key="ListBoxItemStyle" TargetType="ListBoxItem">
<Setter Property="HorizontalContentAlignment" Value="Stretch" />
<Setter Property="HorizontalAlignment" Value="Stretch" />
</Style>
Then the Right alignment of the "Comments" image will work and the central text box will stretch to fill the available space.
You might find that just using a StackPanel with an horizontal orientation works better than a Grid for the item template, especially if the data in columns 0 and 2 are a constant width.

Play around with the space given for the columns, for example:
<Grid.ColumnDefinitions>
<ColumnDefinition Width="67" />
<ColumnDefinition Width="3*"/>
<ColumnDefinition Width="1*" />
</Grid.ColumnDefinitions>
This gives the center column 3 times more space than the right column

It's hard to tell exactly what you want because of how you've blurred your image. But I think the key is to make the container of the grid take up all available space, HorizontalAlignment="Stretch".
<DataTemplate>
<StackPanel HorizontalAlignment="Stretch">
<Grid>
<Grid.ColumnDefinitions>
<ColumnDefinition Width="67" />
<ColumnDefinition Width="*"/>
<ColumnDefinition Width="60" />
</Grid.ColumnDefinitions>
<!-- items here -->
</Grid>
</StackPanel>
The item you set to have Grid.Column="0" will have width 67dip, the one with Grid.Column="2" will be width 60dip, and the one with Grid.Column="1"will fill up the rest of the space.
dip = device independent pixels - all Windows Phone apps are measured as if the screen is 480x800 and then rendered at the actual resolution of the screen.

Inside a StackPanel you can't do HorizontalAlignment to right while its orientation is LeftToRight, as far as I know. Avoid using it.

The problem stems from using a StackPanel as the top-most UIElement. Use a Grid instead and follow the rest of this advice:
Right align content in ListBox
Which leads to this answer as well:
C# windows phone -Alignment in xaml ListBox.ItemTemplate

Your problem is the Button, if it's not mandatory try deleting it and add a "Tap" Event to the StackPanel, i've tried it and it works.
<DataTemplate x:Key="ActivityStreamItemTemplate">
<StackPanel Tap="...">
// no <Button> here
<Grid>
---
</Grid>
// no </Button> here
</StackPanel>
</DataTemplate>
better option
<DataTemplate x:Key="ActivityStreamItemTemplate">
<Grid Tap="...">
...
</Grid>
</DataTemplate>

3 column grid for xaml is not taking up expected space

I have the following xaml:
<DataTemplate x:Key="ActivityStreamItemTemplate">
<StackPanel VerticalAlignment="Top" Margin="5,0,0,0">
<Button Command="{Binding Path=DataContext.LoadSpacesCommand, ElementName=OrganisationList}" CommandParameter="{Binding}" Padding="-5,0,-5,-5" Margin="-7,-12,-7,-7" Height="auto" BorderThickness="0" HorizontalAlignment="Left" VerticalAlignment="Stretch" HorizontalContentAlignment="Left" UseLayoutRounding="True" FontSize="0.01">
<Grid Height="auto">
<Grid.ColumnDefinitions>
<ColumnDefinition Width="67" />
<ColumnDefinition Width="Auto"/>
<ColumnDefinition Width="67" />
</Grid.ColumnDefinitions>
<StackPanel Height="auto" Grid.Column="0" Background="Transparent">
<Border Background="Transparent" BorderThickness="0" Width="62" Height="62" HorizontalAlignment="Left" Margin="0,0,0,5">
<Image Source="{Binding created_by.image.link}" Width="62" Height="62"></Image>
</Border>
</StackPanel>
<StackPanel Height="auto" Grid.Column="1">
<TextBlock Text="{Binding type}" HorizontalAlignment="Left" FontSize="30" VerticalAlignment="Center" Margin="0,0,0,5" Foreground="White" />
<TextBlock Text="{Binding ttitle}" HorizontalAlignment="Left" FontSize="15" VerticalAlignment="Center" Margin="0,0,0,5" Foreground="White" TextWrapping="Wrap" MaxWidth="Infinity" />
<TextBlock Text="{Binding created_by.name}" HorizontalAlignment="Left" FontSize="11" VerticalAlignment="Center" Margin="0,0,0,5" Foreground="White" />
</StackPanel>
<StackPanel Height="auto" Grid.Column="2">
<TextBlock Text="{Binding comment_count}"></TextBlock>
</StackPanel>
</Grid>
</Button>
</StackPanel>
</DataTemplate>
As you can see I would like to have the first column of my grid set to 67.. perfect, and working fine...
The next column needs to fill as much as it can of the screen minus the extra columns width after it.
How do I go about doing this?
Kind of linked to this: How to TextWrap a TextBlock within a width Auto Column? but I couldn't get the * thing to work... I'm not sure it really does what I need it to do

It's because you've got:
MaxWidth="Infinity"
on your TextBlock and
<ColumnDefinition Width="Auto"/>
on your column.
This means that the XAML thinks it can grow that column as much as it likes to fit the text in.
If you want the text to wrap you'll have to provide a limit to either the width of the column, the width of the grid or the width of the stack panel.
If you want the middle column to take the remaining space then just specify it's width with a *:
<ColumnDefinition Width="*"/>